Where Are They Now?

Caroline Dugan (Post-Baccalaureate Academic Fellow)

Latest Work: M.D. Student at Albert Einstein College of Medicine

Caroline Dugan began her journey with Dr. Gobrogge in Fall 2019, utilizing optogenetics in a neuroscience lab at Boston University to study Drosophila behavior. Her experience as a Learning Assistant ignited a passion for teaching, leading her to mentor students in laboratory and discussion sections. After graduating, Caroline worked as a staff instructor, contributing to curriculum development and co-authoring a poster, workshop presentation, and undergraduate STEM pedagogy publication with Drs. Gobrogge & Tullai. Currently, she is a medical student at Albert Einstein College of Medicine, where she continues to leverage the skills and passions developed under Dr. Gobrogge’s mentorship.
Maura Farrell (Independent Study)

Latest Work: Research Assistant in Dr. Deborah J. Anderson’s lab, Chobanian & Avedisian School of Medicine

Maura, in collaboration with Dr. Gobrogge, is conducting a literature review on the history and future of contraception. This review covers the unethical testing on women during the development of the birth control pill, the adverse effects of hormonal contraception, and the need for male contraceptives and Multipurpose Prevention Technologies (MPTs).
Marco Gambino (UROP)

Undergraduate Research
Marco's research on Parkinson's disease involved studying the effects of the cannabinoid CP-55940 on symptoms using Drosophila melanogaster. His experiment, which utilized the Gal4/UAS system to target dopamine transporters, aims to understand the protective potential of cannabinoids against neurotoxicity.
Lara Gardiner (Keystone Kilachand Honors Project)
Latest Work: Napadow Lab at the Spaulding Rehabilitation Center

Lara investigated how serotonin depletion disrupts circadian rhythms in fruit flies and whether sunlight can mitigate this effect. Their study contributes to understanding the relationship between serotonin, circadian rhythms, and potential therapeutic roles of sunlight.
Otto Holbrook (UROP, 2022 Francis Bacon Award for Writing in the Natural Sciences)

Latest Work: Ph.D. Student in Medicinal Chemistry & Drug Discovery, Northeastern University

Otto researched the role of the protein Scabrous in forming alcohol reward memories in Drosophila, focusing on a mutant form that inhibits these memories. His findings could help identify therapeutic targets for Alcohol Use Disorder (AUD).
Sehjin Jo (UROP)

Latest Work: Research Assistant, Laboratory of Dr. Fotios Spyropoulos, Brighman & Women’s Hospital, Harvard Medical School

Sehjin studied the Circadian Rhythm Circuit in Drosophila, using the GAL-4/UAS system for brain mapping and behavior analysis. He is now a Research Assistant at Brigham and Women's Hospital, investigating oxidative stress in neonatal hearts and working as an EMT at Spaulding Rehabilitation Hospital.
Tori Keefauver (UROP, Global Challenge Research Award)

Latest Work: Ph.D. Student in Neuroscience, University of Pittsburgh

Vole Microglia Poster

Tori researched how social isolation impacts microglia in prairie voles as a model for understanding Major Depressive Disorder (MDD). They developed a protocol for immunohistochemistry to compare microglia in bonded and non-bonded voles.
Derek Kolodziejski (UROP)

Latest Work: Research Associate II, Flagship Pioneering, Boston

Derek utilized the Designer Receptors Exclusively Activated by Designer Drugs (DREADD) method to study the roles of D1 and D2 dopamine receptors in alcohol-induced reward conditioned-place-preference using Drosophila melanogaster under the mentorship of Dr. Kyle Gobrogge. His research focused on understanding how receptor modulation affected reward behaviors, contributing to insights into the neural mechanisms involved in conditioned-place-preference.

Currently, Derek works in the biotech industry, actively engaging in small molecule drug discovery. He is part of a pioneering effort at a stealth-stage startup under Flagship Pioneering, where he is developing an innovative chemoproteomics platform targeting oncology and immunology.
Samuel Krick (UROP)

Latest Work: Boston University – Economo Lab Technician

Sam studied the comorbidity of depression and alcoholism in Drosophila by manipulating serotonin transmission using the GAL4/UAS system. He continues his research in the Economo Lab at Boston University, focusing on orofacial motor control.
Muriel Li (UROP)

Latest Work: Continuing Studies

Muriel explored how serotonin affects social reactions in fruit flies and studied the developmental role of the steroid hormone ecdysone.
Mattie Love (UROP)

Latest Work: Continuing Studies

Mattie assessed the effectiveness of Drosophila Activity Monitors (DAMs) in a preference assay, exploring flies' choices between food options and their ethanol preferences, demonstrating the viability of DAMs in behavioral research.
Eddie Miller (UROP)

Latest Work: Clinical Research Study Assistant in the Laboratory of Scott Marek at University of Washington School of Medicine – St. Louis, MO

Eddie investigated how manipulating the gut microbiome affects serotonin usage in the brain using Drosophila, aiming to understand the gut-brain axis's impact on brain function through genetic manipulation.
Brandon Molligoda (UROP Supplies Award, 2022 Francis Bacon Award for Writing in the Natural Sciences)

Latest Work: M.D. Student, University of Central Florida

Brandon focused on the protein scabrous and its role in forming alcohol-induced reward memories in Drosophila. His work also included a review on the behavioral implications of ethanol metabolism in alcohol use disorder.
Shreya Nandyala (Independent Study)

Latest Work: Student at University of California – Berkeley

Shreya reviewed the effects of music therapy and meditation on cognitive decline, highlighting their benefits in reducing stress and improving quality of life.
Josh Rong (UROP)

Latest Work: Clinical Research Assistant, Boston Children’s Hospital, Harvard Medical School

Josh extended his classroom project on octopamine and Drosophila during a summer UROP. He now focuses on Neurological Movement Disorders at Boston Children’s Hospital, particularly Hereditary Spastic Paraplegia.
LJ Ullman (UROP Supplies Award)

Latest Work: M.D. Student, Lewis Katz School of Medicine

LJ investigated the role of scabrous in forming long-term alcohol reward memories in Drosophila, focusing on how mutant variants affect behavior and anatomical expression.
Rhea Singh (Independent Study)

Latest Work: Research Technician, Laboratory of Dr. Richard Axel under the direction of Postdoctoral Fellow Dr. Jennifer Bussell, Columbia University.

Rhea Singh investigated the neural circuits responsible for aggression in rodents, focusing on olfactory systems and their links to the prefrontal cortex. This work sheds light on how sensory cues can trigger aggressive behaviors and discusses potential interventions for aggression disorders. Her findings emphasize the complexity of aggression circuits and suggest novel therapeutic strategies.
Lily Tong (Directed Study)

Latest Work: Incoming Ph.D. Student, Psychological & Brain Sciences, Dartmouth College (van der Meer Lab)

Lily Tong studied the effects of dysbindin gene mutations on movement frequency in Drosophila and later worked as a Research Technician in Dr. Mark Howe’s Lab at Boston University, investigating the striatum’s role in visually guided movements. Her work bridges genetic models of schizophrenia and systems neuroscience approaches to decision-making and behavior.
Indu Vaddiparti (Independent Study)

Latest Work: D.O. Student, Virtua Health College of Medicine & Life Sciences, Rowan University  

Indu reviewed neuroscientific research on sexual orientation among neurodivergent populations, focusing on increased sexual fluidity in individuals with Down Syndrome and Autism Spectrum Disorder.
Andrew White (Learning Assistant)

Latest Work: M.D. Student at NYU Grossman School of Medicine

Andrew White's collaboration with Dr. Gobrogge began during his sophomore year while studying the use of Drosophila in neuroscience. Inspired by this work, Andrew served as a Learning Assistant, teaching and guiding new students in essential laboratory skills. After graduating, he spent two years at Brigham and Women’s Hospital researching Parkinson’s Disease, applying techniques learned from Dr. Gobrogge. He also delivered a guest lecture on his findings at Dr. Gobrogge's invitation. Andrew is currently a medical student at NYU Grossman School of Medicine, continuing to apply his learning and experiences from his time with Dr. Gobrogge.
Ziyu (Ivan) Zhao (Independent Study)

Latest Work: Ph.D. Student, Clinical Psychology, Laboratory of Dr. Pamela Keel, Florida State University

Ivan reviewed the interplay between sex hormones, personality traits, and eating disorders, suggesting potential mediating roles of personality and proposing further research using comprehensive personality assessments and neuroimaging techniques.
RISE Program
Research in Science & Engineering (RISE) is a program for students passionate about the sciences in their junior year of high school. Students spend six weeks at Boston University conducting laboratory research and advancing their STEM knowledge and skills.

2024 Cohort

Shreya Ambekar

Latest Work: Continuing Studies

Shreya investigated the role of octopamine in anesthetic vulnerability in Drosophila melanogaster, utilizing optogenetic tools to modulate octopamine neuron activity. By employing the GAL4/UAS system, she found that acute activation of octopamine neurons reduced anesthetic susceptibility and increased aversion, while deactivation had no significant effect. These findings underscore the potential influence of norepinephrine levels and arousal states in anesthetic administration, offering insights for more personalized approaches in clinical anesthesia.
Cyan Ding

Latest Work: Continuing Studies

Cyan's research explored the effects of sex-specific modulation of serotonin neurons on depression-like behaviors in Drosophila, utilizing optogenetics. The study found significant differences in how male and female flies responded to induced depression, highlighting the role of serotonin in these behavioral differences.
Daniel Goo

Latest Work: Student at Princeton University

RISE Research
Daniel explored the effects of acutely activating and inactivating cholinergic neurons in fruit flies, aiming to understand neurotransmitter roles in movement and their implications for neurodegenerative diseases.
Kimia Habibzadeh
Latest Work: Continuing Studies

RISE Research
Kimia examined the role of dopamine in feeding behavior among Drosophila, using optogenetic techniques to modulate dopamine levels. This research contributes to understanding the neural mechanisms underlying eating disorders and obesity, demonstrating that dopamine modulation does not directly influence short-term food consumption.
Izabelle Kokkat

Latest Work: Continuing Studies

RISE Research
Izabelle's project involved studying the effects of optogenetic modulation of serotonin neurons on the behavioral states of restrained Drosophila. The findings indicate that serotonin modulation impacts the activity-inactivity ratios and state-switching behaviors of flies, providing insights into the neural basis of stress and trauma responses.

2023 Cohort

Maggie Zhou

Latest Work: Student at Massachusetts Institute of Technology

RISE Research
Maggie studied the role of dopamine neurons in sleep-wake cycles of fruit flies, modeling sleep disturbances seen in Parkinson's disease, suggesting new research avenues for understanding PD-related sleep issues.

2022 Cohort

Julia Banuelos

Latest Work: Student at Dartmouth College

RISE Research
Julia focused on the role of octopamine neurons in heterospecific aggression in Drosophila, using light to acutely inhibit these neurons and observing behavioral responses.
Ashley Deng

Latest Work: Student at Rice University

RISE Research
Ashley proposed a model for the latency period in antidepressant treatment using fruit flies, exploring the role of 5-HT1A autoreceptors in delaying the effectiveness of antidepressants.
Layla Manaswini Palutla

Latest Work:
B.S.-M.D. Student at University of Colorado, Denver

RISE Research
Layla investigated the role of choline acetyltransferase in olfactory reception in Drosophila, using genetic manipulation to study changes in olfaction and potential drug targets for neurodegenerative diseases.

2021 Cohort

Vedanti Bhargava
Shreya Kaushik
Vedanti Bhargava & Shreya Kaushik

Vedanti's Latest Work: Student at Johns Hopkins University
Shreya's Latest Work: Student at Georgetown University

RISE Research
Vedanti and Shreya researched the roles of neuropeptide F and its receptors in Drosophila behavior, highlighting the need for further research into NPF's role in sleep, courtship, and feeding behaviors.